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KMID : 0881720170320030187
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Journal of Food Hygiene and Safety
2017 Volume.32 No. 3 p.187 ~ p.192
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Preliminary Monitoring of Mycotoxins for Safety Management of Medicinal Herbs
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Lee Hyun-Kyung
Kim Ae-Kyung
Kim Ouk-Hee
Kim Sung-Dan
Lee Young-Ju
Lee Sae-Ram
Kim Il-Young
Lee Jeong-Mi
Yoo In-Sil
Jung Kweon
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Abstract
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The consumption of herbal medicines has been increasing with growing interest in health. However, due to recent climate change and the complex distribution process of herbal medicines with high import dependence the likelihood of contamination with mycotoxin has been increased. Mycotoxins are emerging as key indicators for ensuring safety of herbal medicines. A total of 498 herbal medicine samples were screened for mycotoxin contamination in this study. Aflatoxin in the herbal medicine samples was extracted by using immunoaffinity column, then the extracted aflatoxin was quantified via high performance liquid chromatography coupled with fluorescence detection (HPLC-FLD) method. The extraction method was verified by linearity, recovery, LOD and LOQ. Aflatoxins were detected in 39/498 samples in an average of 7.670 μg/kg (0.610-77.452 μg/kg range). Although safety standards for Corydalis Tuber is not currently available in korea, five of the 39 samples had high concentration of aflatoxins (average of 14.9 ± 4.1 μg/kg). In conclusion, it is urgent to establish safety criteria of aflatoxin in Corydalis Tuber. The results of the current study suggest that continuous monitoring is necessary for proactive management of herbal medicine safety.
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KEYWORD
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Herbal medicines , HPLC-FLD , Aflatoxin , Corydalis Tuber
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